N Acetyl L Cysteine: Is not That Tough As You Assume > 자유게시판

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Although the presently most popular embodiment of the invention contemplates the use of the phosphodiesterase inhibitor sildenafil citrate as the preferred lively for the methods set forth herein within the remedy and/or prevention of EIPH, it is particularly contemplated that other phosphodiesterase inhibitors are within the scope of the invention. In particular, the invention pertains to methods and units for nebulization therapy in horses for the remedy and prevention of respiratory circumstances including Exercise-Induced Pulmonary Hemorrhage (EIPH) and related pulmonary sequella within the horse. The foregoing and other objects, features and benefits of the present invention should become apparent to those of talent within the art in the following description when taken along side the accompanying drawings and by way of observe of the invention. Accordingly, there nonetheless exists a need within the art for such strategies. Within the embodiment shown, in FIG. 1, the device 10 and attachment means 20 are proven hooked up to the pinnacle 30 of the topic equine and mendacity beneath a regular equine halter 60. Thus, one among talent within the artwork can appreciate that the gadget 10 and attachment means 20 can be hooked up and used unbiased of however in conjunction with halters, bridles or other equine head gear.

In the embodiment shown in FIG. 1, the attachment means 20 itself is a halter-type or halter-like apparatus constructed of nylon or leather with adjustable straps for securing to the pinnacle 30 of the topic equine and is separate from halter 60. As set forth extra filly below, the attachment means 20 for the system 10 might be separate from halter 60 or built-in therein. The device 10 or equine nasal cannula may be designed to conform to or become an integral a part of harness and/or bridle or different halter-kind equipment normally associated with the training and racing of equine athletes. Thus, the current invention gives an inhalation therapy regimen administered by, e.g., a non-invasive equine nasal cannula machine as also offered by the invention. In a presently most popular embodiment, the invention provides a technique for the remedy or prevention of EIPH, wherein the composition for inhalant therapy is a mixture comprised of sildenafil citrate or its congeners (e.g., metabolites, isomers, salts or different active derivatives of sildenafil citrate) utilizing air as the delivery automobile to carry the inhalant into the equine mammal. In a single embodiment, the therapy regimen includes the introduction of a composition comprised of sildenafil citrate or congeners of sildenafil citrate with or with out potentiating agents delivered to the topic equine via the attendant inhalation therapy system in a non-invasive manner that's conducive to the care and comfort of the equine mammal below treatment.

The gadget 10 is held in position by attachment means 20 such that the distal ends 16, 18 of elongated delivery tubes 12, 14 (cannulas) are placed adjacent the exterior openings 32, 34 of the topic equine's nasal cavity (adjacent the nares) so as to successfully deliver the composition chosen for inhalation at the appropriate site. In the presently most well-liked embodiment, the device 10 of the invention (the equine nasal cannula) is comprised of a nylon attachment means 20 (similar to a halter) that is configured to adapt to the contours of the equine skull 30 in such a manner as to effectively place and hold the distal ends 16, 18 of the elongated delivery tubes 12, 14 in a desired position for the administration of a therapeutic inhalant while minimizing the requirements for specialised animal restraint and/or restriction of motion. In one embodiment, padded extrusions (not shown) are provided on the distal ends 16, 18 (nasal finish) of the elongated tubes 12, 14 (cannulas) to stop injury or irritation that will happen from rubbing the nostrils or the inside linings (mucosa) of the nostrils.

Thus, the dimensional and other characteristics shown in FIGS. FIG. 5 is a perspective view of 1 embodiment of the nebulization apparatus and air supply for delivery of a desired therapeutic agent by way of the device of FIGS. FIG. Three is a perspective view of one embodiment of the nasal cannula portion of the machine of the invention. FIG. 7 is a shade digital photograph showing a left frontal view of 1 embodiment of the system of the invention. It's an object of the invention to supply an inhalation therapy regimen and system for the treatment and/or prevention of EIPH comprising the inhalation of a therapeutic amount of sildenafil citrate and/or the metabolites of sildenafil citrate alone or in combination with different compounds. Studied for its immune health benefits, N-Acetyl-L-Cysteine 98% bulk suppliers defends in opposition to insults from international compounds. Generally talking, easy organic compounds formed by the substitute of a hydrogen atom of hydrogen sulfide by an aliphatic, aromatic or heterocyclic radical are known as "thiols," e.g. methanethiol; whereas, polyfunctional compounds so formed are sometimes described with the prefix "mercapto," reminiscent of mercaptoacetic acid.